WHEREAS, Adenomatous polyposis coli (APC)-associated polyposis, which includes familial adenomatous polyposis (FAP), is a hereditary condition that results in high number of polyps developing within the colon and rectum, significantly increasing an individuals risk of colorectal cancer; and

WHEREAS, Genetic changes in the APC gene related to FAP leads to the development of hundreds of polyps within the colon, frequently beginning during an individuals teenage years, that, if left untreated, leads to cancer developing, on average, by 39 years of age; and

WHEREAS, Attenuated familial adenomatous polyposis (AFAP) is a variant of the condition, that causes fewer polyps to develop at a later age, with an average cancer diagnosis of 55 years of age if left untreated; and

WHEREAS, Undiagnosed FAP and AFAP can increase the risk of cancer to develop in the stomach, small intestine, liver, brain, thyroid, and pancreas and can cause other health conditions, including osteomas and desmoid tumors; and

WHEREAS, Having a sibling, parent, or child with the condition increases an individuals risk of FAP or AFAP. Knowing your family health history and discussing it with your health care provider can help determine if genetic counseling or genetic testing would be appropriate; and

WHEREAS, Understanding your risk for FAP or AFAP can help a health care provider determine an appropriate treatment and screening protocol for the prevention or early detection of colorectal and other cancers; and

WHEREAS, During this week, the Stanford University Department of Health Policy joins with the Stanford Genetics and Genomics Program and the Stanford Cancer Center to raise awareness of FAP and AFAP. California residents are encouraged to gather their family health history and share that information with their health care provider for early screening and prevention of cancers associated with these conditions; now, therefore, be it

Resolved by the Senate of the State of California, That the Senate hereby proclaims the week of June 16, 2026, to June 22, 2026, inclusive, as Familial Adenomatous Polyposis Awareness Week in California; and be it further

Resolved, That the Secretary of the Senate transmit copies of this resolution to the author for appropriate distribution.

SR 112

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